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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1988-1-28
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pubmed:abstractText |
The influence of prednisolone on the elimination of antipyrine has been investigated. The one-sample antipyrine clearance was estimated in 23 outpatients with obstructive lung disease before and after treatment with prednisolone 30 or 50 mg/day for 7 days. During prednisolone administration antipyrine clearance decreased from 54.9 +/- 14.8 to 51.7 +/- 14.6 ml/min (mean +/- SD; p less than 0.05). The results indicate that prednisolone decreases the rate of antipyrine elimination, but not to an extent suggesting a clinically important change in hepatic drug metabolism.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0031-6970
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
33
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
89-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3691602-Antipyrine,
pubmed-meshheading:3691602-Female,
pubmed-meshheading:3691602-Humans,
pubmed-meshheading:3691602-Liver,
pubmed-meshheading:3691602-Lung Diseases, Obstructive,
pubmed-meshheading:3691602-Male,
pubmed-meshheading:3691602-Metabolic Clearance Rate,
pubmed-meshheading:3691602-Middle Aged,
pubmed-meshheading:3691602-Prednisolone
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pubmed:year |
1987
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pubmed:articleTitle |
Influence of prednisolone on antipyrine elimination in patients with obstructive lung disease.
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pubmed:affiliation |
Medical Department F, Gentofte University Hospital, Hellerup, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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