Linked Life Data

3691067

Source:http://linkedlifedata.com/resource/pubmed/id/3691067

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1988-2-10
pubmed:abstractText
The distribution profile of resistance in a series lung model consisting of airways of 23 generations with alveoli was estimated in 10 healthy subjects and 7 subjects with chronic pulmonary emphysema. Forced oscillation was applied to the subjects at the mouth using a complex wave composed of sine waves at frequencies through the range 4 to 20 Hz in 1-Hz steps. The pleural pressure was measured with a catheter-tip micromanometer, which was installed in an esophageal balloon. The frequency dependency of the pulmonary impedance was analyzed using a penalty function method, and a stable estimate of the distribution profile of resistance in the lungs was thus obtained. The central airway resistance (defined as the resistance from generation 0 to generation 7) was estimated as 1.18 +/- 0.37 cm H2O/liter/sec in the healthy subjects and 1.03 +/- 1.13 cm H2O/liter/sec in the subjects with chronic pulmonary emphysema. The peripheral airway resistance (defined as the resistance from generation 8 to generation 23) was estimated as 0.06 +/- 0.03 cm H2O/liter/sec in the healthy subjects and 6.38 +/- 3.77 cm H2O/liter/sec in the subjects with chronic pulmonary emphysema.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0010-4809
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
507-25
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Estimation of the distribution profile of airway resistance in the lungs.
pubmed:affiliation
Department of Medicine, School of Medicine, Keio University, Tokyo, Japan.
pubmed:publicationType
Journal Article