Linked Life Data

3688494

Source:http://linkedlifedata.com/resource/pubmed/id/3688494

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1988-1-4
pubmed:abstractText
The low solubility and high stability of the new volatile anesthetic, I-653, suggest that this agent should have little or no toxic effect. This hypothesis was tested using repeated exposures to I-653, to isoflurane, or to no anesthetic. For 2 consecutive weeks, groups of 16 rats each were subjected to a total of six 2-hr exposures to 100% oxygen and 1.6 MAC I-653, isoflurane, or no anesthetic. Twenty-four hours after the last exposure, the rats were killed by administration of 100% carbon dioxide and then autopsied. Specimens were taken from brain, pituitary, lung, heart, duodenum, pancreas, kidney, and liver. No tissue damage attributable to either anesthetic was found nor was weight gain affected.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-2999
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1230-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Comparison of the toxicity of I-653 and isoflurane in rats: a test of the effect of repeated anesthesia and use of dry soda lime.
pubmed:affiliation
Department of Anesthesia, University of California, San Francisco 94143-0542.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't