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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1987-12-21
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pubmed:abstractText |
Sixty out of 63 patients with insulin-dependent diabetes mellitus (IDDM) diagnosed during pregnancy in the Diabetes Centre at the Department of Obstetrics and Gynaecology, Rigshospitalet, Copenhagen, were re-examined 2-16 years after diagnosis. Fourty-six patients were currently insulin-treated and the remaining 14 patients were all severely glucose intolerant. HLA-typing was carried out in 41 of these patients. The HLA phenotype distribution showed a highly significant difference from that of non-diabetics but was similar to that seen in IDDM not related to pregnancy. Thus, pregnancy may constitute a special trigger mechanism for IDDM, but the subsequent pathogenic mechanisms are probably the same as those involved in other cases of IDDM.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0001-5598
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
387-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3687322-Diabetes Mellitus, Type 1,
pubmed-meshheading:3687322-Female,
pubmed-meshheading:3687322-Follow-Up Studies,
pubmed-meshheading:3687322-HLA Antigens,
pubmed-meshheading:3687322-HLA-D Antigens,
pubmed-meshheading:3687322-Humans,
pubmed-meshheading:3687322-Phenotype,
pubmed-meshheading:3687322-Pregnancy,
pubmed-meshheading:3687322-Pregnancy in Diabetics
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pubmed:year |
1987
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pubmed:articleTitle |
HLA associations in insulin-dependent diabetes mellitus diagnosed during pregnancy.
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pubmed:affiliation |
Hvidøre Hospital, Klampenborg, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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