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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1988-1-7
|
| pubmed:abstractText |
This is a retrospective study of 28 infants and children with Dandy-Walker syndrome: 16 had a complete postmortem examination and 12 are currently being followed clinically. Eleven of sixteen in the first category had hydrocephalus; 10 of those 11 had other central nervous system malformations, and 6 also had visceral anomalies. Four of the five without hydrocephalus had complex cardiac malformations and other visceral anomalies whereas 1 died as a consequence of acute myelogenous leukemia. The 12 children still under surveillance manifest no clinical evidence of significant visceral or central nervous system malformation, although 1 has CT scan evidence of agenesis of the corpus callosum. The majority (9/12) of these children have normal intelligence although 40% have focal neurologic deficits or gait abnormalities and 60% have an abnormal EEG. Frequent association of other malformations and/or visceral anomalies in children with Dandy-Walker syndrome make it difficult to propose a unifying hypothesis relative to embryogenesis of the syndrome.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0255-7975
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
38-44
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3684814-Abnormalities, Multiple,
pubmed-meshheading:3684814-Adolescent,
pubmed-meshheading:3684814-Adult,
pubmed-meshheading:3684814-Autopsy,
pubmed-meshheading:3684814-Brain,
pubmed-meshheading:3684814-Cerebrospinal Fluid Shunts,
pubmed-meshheading:3684814-Child,
pubmed-meshheading:3684814-Child, Preschool,
pubmed-meshheading:3684814-Dandy-Walker Syndrome,
pubmed-meshheading:3684814-Female,
pubmed-meshheading:3684814-Humans,
pubmed-meshheading:3684814-Hydrocephalus,
pubmed-meshheading:3684814-Infant,
pubmed-meshheading:3684814-Intelligence Tests,
pubmed-meshheading:3684814-Male,
pubmed-meshheading:3684814-Neurologic Examination,
pubmed-meshheading:3684814-Retrospective Studies,
pubmed-meshheading:3684814-Tomography, X-Ray Computed
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Dandy-Walker syndrome and associated anomalies.
|
| pubmed:affiliation |
University of Pennsylvania, School of Medicine, Philadelphia.
|
| pubmed:publicationType |
Journal Article
|