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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1988-1-11
|
| pubmed:abstractText |
The outcome of infants born to cocaine-using drug dependent women was compared to that of infants of non-cocaine using drug dependent and non-drug dependent women. The study population included 150 pregnant women: 50 women used heroin and methadone plus cocaine, 50 used heroin and methadone minus cocaine, and 50 were non-drug dependent women. Significant differences were found between the cocaine and drug-free groups in infant birth weight, length, head circumference and Apgar scores, with the cocaine group having lower values for each variable. Average gestational age did not vary between the 3 groups. The cocaine group included 1 spontaneous abortion and 4 fetal deaths; non-cocaine drug dependent women had 2 fetal deaths, with none in the control group. Mean abstinence scores for 19 of the physiological and behavioral parameters were lower in the cocaine group than in the non-cocaine drug dependent women with the exception of vomiting and convulsions. These data suggest that: (1) infants born to drug dependent women have a poorer general outcome than those born to non-drug dependent women; (2) maternal cocaine use does not appear to increase the incidence of severe neonatal abstinence symptomatology; (3) pregnancies complicated by cocaine abuse have a greater chance for fetal loss resulting from both spontaneous abortions and fetal death; (4) infants born to cocaine abusing women had infants with decreased birth weight, head circumference, length and Apgar scores.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0892-0362
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
9
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
295-9
|
| pubmed:dateRevised |
2009-10-26
|
| pubmed:meshHeading |
pubmed-meshheading:3683347-Cocaine,
pubmed-meshheading:3683347-Female,
pubmed-meshheading:3683347-Fetus,
pubmed-meshheading:3683347-Humans,
pubmed-meshheading:3683347-Infant, Newborn,
pubmed-meshheading:3683347-Methadone,
pubmed-meshheading:3683347-Neonatal Abstinence Syndrome,
pubmed-meshheading:3683347-Pregnancy,
pubmed-meshheading:3683347-Substance-Related Disorders
|
| pubmed:articleTitle |
Cocaine abuse in pregnancy: effects on the fetus and newborn.
|
| pubmed:affiliation |
Jefferson Medical College of Thomas Jefferson University, Department of Pediatrics, Philadelphia, PA 19107.
|
| pubmed:publicationType |
Journal Article
|