Linked Life Data

3677060

Source:http://linkedlifedata.com/resource/pubmed/id/3677060

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-1-12
pubmed:abstractText
Mangiferin, a naturally occurring glucosylxanthone, was assessed for its immunomodulatory potential. The phytochemical induced extensive in vitro proliferation of murine splenocytes and thymocytes at the doses of 5-40 micrograms ml-1. Suppression of the proliferative response of the cells was observed with higher doses of mangiferin. Mangiferin also activated the splenocytes of tumor hosts at early and late stages of tumor growth. The Phytohemagglutinin (PHA) and Con A unresponsive splenocytes of advanced tumor bearer proliferated extensively in response to mangiferin. Mangiferin when used with Con A produced additive stimulatory effect and induced heightened DNA synthesis of normal and advanced tumor bearers' splenocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0304-3835
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
293-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Activation of lymphocytes of normal and tumor bearing mice by mangiferin, a naturally occurring glucosylxanthone.
pubmed:affiliation
Department of Tumor Immunobiology, Chittaranjan National Cancer Research Centre, Calcutta, India.
pubmed:publicationType
Journal Article, In Vitro