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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1987-12-11
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pubmed:abstractText |
The effects of dietary supplementation with selenium were studied in 6 patients with severe, active rheumatoid arthritis (RA) and in 6 healthy control subjects. Initial concentrations of Se in red blood cells and in serum, and the activity of the Se-dependent enzyme glutathione peroxidase (GSH-Px) in red blood cells, serum, and granulocytes were significantly lower in RA patients compared with controls. During Se supplementation, however, the differences in Se levels and in GSH-Px activity between the 2 groups disappeared, except that, in RA patients, GSH-Px activity in granulocytes increased but remained significantly lower than in controls.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1162-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3675661-Adult,
pubmed-meshheading:3675661-Aged,
pubmed-meshheading:3675661-Arthritis, Rheumatoid,
pubmed-meshheading:3675661-Erythrocytes,
pubmed-meshheading:3675661-Female,
pubmed-meshheading:3675661-Glutathione Peroxidase,
pubmed-meshheading:3675661-Granulocytes,
pubmed-meshheading:3675661-Humans,
pubmed-meshheading:3675661-Male,
pubmed-meshheading:3675661-Middle Aged,
pubmed-meshheading:3675661-Reference Values,
pubmed-meshheading:3675661-Selenium
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pubmed:year |
1987
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pubmed:articleTitle |
Glutathione peroxidase activity in patients with rheumatoid arthritis and in normal subjects: effects of long-term selenium supplementation.
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pubmed:affiliation |
Rheumatism Research Unit, Orthopaedic Hospital, University of Aarhus, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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