|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0008662,
umls-concept:C0017337,
umls-concept:C0024779,
umls-concept:C0086418,
umls-concept:C0162326,
umls-concept:C0175723,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C1412365,
umls-concept:C1552599,
umls-concept:C1704787
|
|
pubmed:issue |
Pt 2
|
|
pubmed:dateCreated |
1987-12-17
|
|
pubmed:abstractText |
A human placental alkaline phosphatase (PLAP) cDNA was isolated from a lambda gt 10 library of the cell line HEp-2. Southern blots probed with a fragment of the cDNA clone showed that the human genome may contain more than one PLAP-related sequence. The PLAP probe showed person-to-person variation in banding pattern with a number of enzymes. Using a panel of human/rodent somatic cell hybrids the PLAP sequences were mapped to chromosome 2. In situ hybridization confirmed this assignment and localized the gene(s) to chromosome 2 band q37.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0003-4800
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
51
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
145-52
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:3674755-Alkaline Phosphatase,
pubmed-meshheading:3674755-Animals,
pubmed-meshheading:3674755-Chromosome Mapping,
pubmed-meshheading:3674755-Chromosomes, Human, Pair 2,
pubmed-meshheading:3674755-DNA,
pubmed-meshheading:3674755-GPI-Linked Proteins,
pubmed-meshheading:3674755-Genes,
pubmed-meshheading:3674755-Humans,
pubmed-meshheading:3674755-Hybrid Cells,
pubmed-meshheading:3674755-Isoenzymes,
pubmed-meshheading:3674755-Nucleic Acid Hybridization,
pubmed-meshheading:3674755-Polymorphism, Genetic
|
|
pubmed:year |
1987
|
|
pubmed:articleTitle |
The human placental alkaline phosphatase gene and related sequences map to chromosome 2 band q37.
|
|
pubmed:affiliation |
Imperial Cancer Research Fund, Lincoln's Inn Fields, London.
|
|
pubmed:publicationType |
Journal Article
|
