Linked Life Data

3673612

Source:http://linkedlifedata.com/resource/pubmed/id/3673612

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-12-14
pubmed:abstractText
The study was undertaken to identify possible ultrastructural changes occurring in pancreatic duct cells in relation to secretin-dependent NaHCO3 secretion, Pancreatic biopsies were obtained for examination, following in situ glutaraldehyde fixation from four groups of anaesthetized, young pigs. In the resting state, pancreatic duct cell cytoplasm was found to contain multiple vesicles of approximately 0.2 micron diameter. Elevation of systemic arterial PCO2 to 11.1 (10.6-11.6) kPa increased the number of vesicles per unit volume of resting cells by approximately 250%. During secretin-dependent NaHCO3 secretion, the duct cell cytoplasm was devoid of vesicles. Following cessation of secretin-dependent NaHCO3 secretion, cytoplasmic vesicles reappeared. The observed changes in the population of cytoplasmic vesicles in pancreatic duct cells may be causally related to the exocrine secretion of NaHCO3.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0001-6772
pubmed:author
pubmed:issnType
Print
pubmed:volume
131
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Ultrastructure of pancreatic duct cells at secretory rest and during secretin-dependent NaHCO3 secretion.
pubmed:affiliation
University of Oslo, Institute for Experimental Medical Research, Ullevaal Hospital, Norway.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't