Linked Life Data

3672033

Source:http://linkedlifedata.com/resource/pubmed/id/3672033

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1987-12-16
pubmed:abstractText
Different possibilities to predict infarct size were analysed. The basic method was the fitting of a mathematical model to serial serum myoglobin concentration values from the very early phase of infarction. Correlation was performed with infarct size estimated from the complete serum curves of 53 patients. An observation period up to and including the serum peak value (on the average 6.8 h after onset) was required in order to give a well-determined value of infarct size. A correlation coefficient of r = 0.85 (n = 38) was then obtained. The serum peak concentration value of myoglobin correlated even better (r = 0.89). The initial slope of the serum curve (obtained on the average 4.3 h after onset of symptoms) also correlated well to infarct size (r = 0.80; n = 53). In conclusion, estimation of infarct size appears to be as good with the serum peak value of myoglobin as with model-based parameters. The most useful measure for early prediction of infarct size could be the initial slope of the serum curve.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0036-5513
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
599-603
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Prediction of myocardial infarct size from early serum myoglobin observations.
pubmed:affiliation
Unit of Biomedical Systems Analysis, Uppsala University, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't