Linked Life Data

3667427

Source:http://linkedlifedata.com/resource/pubmed/id/3667427

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1987-11-30
pubmed:abstractText
Quantitative methods for the determination of the concentration, percent motility and swimming speed of human and animal spermatozoa can assist in the objective analysis of sperm and semen quality. These parameters are among the most discriminating indicators for both clinical and toxicologic assessments of reproductive function. A computerized videomicrographic analysis system to measure sperm motility characteristics in the Fischer 344 rat was characterized and compared with both manual and semi-automated videomicrographic methods (Blazak et al, 1985). The system compares favorably, both in accuracy and sensitivity, to these more conventional methods. The most variable indicator of potential reproductive function in the Fischer 344 rat is the total sperm count from the cauda epididymidis (coefficient of variation [CV] = 24%), while parameters of sperm motility vary least. These include percentage of motile cells (CV = 15%), curvilinear velocity (CV = 9%) and linearity (CV = 10%), which is a ratio of straight-line to total distance traveled. It was concluded that the computerized system may be useful for routine assessment of changes in sperm quality that may occur in the rat after exposure to toxic drugs or chemicals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0196-3635
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
330-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Computerized videomicrographic analysis of rat sperm motility.
pubmed:affiliation
Department of Genetic Toxicology, Chemical Industry Institute of Toxicology, Research Triangle Park, North Carolina 27709.
pubmed:publicationType
Journal Article, Comparative Study