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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-11-24
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pubmed:databankReference | |
pubmed:abstractText |
The contents of the mRNAs encoding the gamma- and epsilon-subunits of the nicotinic acetylcholine receptor as well as the single-channel properties of the receptor have been assessed in innervated, denervated and reinnervated rat muscle. The changes in abundance of the gamma- and epsilon-subunit mRNAs correlate with the changes in relative density of two classes of acetylcholine receptor channels. The results support the view that a switch in the relative abundance of the gamma- and epsilon-subunit mRNAs is a major mechanism in regulating the properties of acetylcholine receptor channels in muscle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
223
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3666131-Amino Acid Sequence,
pubmed-meshheading:3666131-Animals,
pubmed-meshheading:3666131-Base Sequence,
pubmed-meshheading:3666131-Diaphragm,
pubmed-meshheading:3666131-Gene Expression Regulation,
pubmed-meshheading:3666131-Molecular Sequence Data,
pubmed-meshheading:3666131-Muscle Denervation,
pubmed-meshheading:3666131-RNA, Messenger,
pubmed-meshheading:3666131-Rats,
pubmed-meshheading:3666131-Receptors, Nicotinic
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pubmed:year |
1987
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pubmed:articleTitle |
Differential regulation of muscle acetylcholine receptor gamma- and epsilon-subunit mRNAs.
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pubmed:affiliation |
Abteilung Neurochemie, Max-Planck-Institut für biophysikalishe Chemie, Göttingen, FRG.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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