Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1987-11-23
|
pubmed:abstractText |
Information was obtained on the living status or cause of death of 2223 close relatives of 195 children with soft-tissue sarcomas (STS) diagnosed under age 15. Three-hundred nine relatives had died, from all causes, before STS diagnosis in the index child. The expected figure estimated from age- and sex-specific mortality rates in Italy was 293.3. Cancer was reported as cause of death in 76 relatives (75.1 expected). Seven grandmothers, 2 aunts, 1 uncle and 0 mothers died from breast cancer vs. 4.6, 0.9, 0.0 and 0.2 expected. Three siblings died from cancer (0.2 expected, P less than 0.01), i.e. STS, ependymoma and non-Hodgkin lymphoma. These results confirm and expand previous observations that STS in children are associated with other cancers, particularly childhood and breast cancer, in members of the same family.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0304-3835
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
37
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
17-24
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3664449-Adolescent,
pubmed-meshheading:3664449-Adult,
pubmed-meshheading:3664449-Age Factors,
pubmed-meshheading:3664449-Child,
pubmed-meshheading:3664449-Child, Preschool,
pubmed-meshheading:3664449-Female,
pubmed-meshheading:3664449-Health Surveys,
pubmed-meshheading:3664449-Humans,
pubmed-meshheading:3664449-Infant,
pubmed-meshheading:3664449-Italy,
pubmed-meshheading:3664449-Male,
pubmed-meshheading:3664449-Middle Aged,
pubmed-meshheading:3664449-Pedigree,
pubmed-meshheading:3664449-Retrospective Studies,
pubmed-meshheading:3664449-Rhabdomyosarcoma,
pubmed-meshheading:3664449-Sarcoma,
pubmed-meshheading:3664449-Sex Factors,
pubmed-meshheading:3664449-Soft Tissue Neoplasms
|
pubmed:year |
1987
|
pubmed:articleTitle |
Cancer mortality among relatives of children with soft-tissue sarcoma: a national survey in Italy.
|
pubmed:affiliation |
Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|