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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1987-11-20
|
| pubmed:abstractText |
To determine the clinical evolution of Lyme arthritis, 55 patients who did not receive antibiotic therapy for erythema chronicum migrans were followed longitudinally for a mean duration of 6 years. Of the 55 patients, 11 (20%) had no subsequent manifestations of Lyme disease. From 1 day to 8 weeks after disease onset, 10 of the patients (18%) began to have brief episodes of joint, periarticular, or musculoskeletal pain for as long as 6 years, but they never developed objective joint abnormalities. From 4 days to 2 years after disease onset, 28 (51%) had one episode or began to have intermittent attacks of frank arthritis, primarily in large joints; a few had polyarticular movement. The total number of these patients who continued to have recurrences decreased by 10% to 20% each year. The remaining 6 patients (11%) developed chronic synovitis later in the illness; of these, 2 (4%) had erosions, and 1 (2%), permanent joint disability. The spectrum of Lyme arthritis ranges from subjective joint pain, to intermittent attacks of arthritis, to chronic erosive disease.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0003-4819
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
107
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
725-31
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3662285-Adolescent,
pubmed-meshheading:3662285-Adult,
pubmed-meshheading:3662285-Anti-Bacterial Agents,
pubmed-meshheading:3662285-Arthritis, Infectious,
pubmed-meshheading:3662285-Child,
pubmed-meshheading:3662285-Child, Preschool,
pubmed-meshheading:3662285-Chronic Disease,
pubmed-meshheading:3662285-Connecticut,
pubmed-meshheading:3662285-Erythema,
pubmed-meshheading:3662285-Female,
pubmed-meshheading:3662285-Humans,
pubmed-meshheading:3662285-Joint Diseases,
pubmed-meshheading:3662285-Lyme Disease,
pubmed-meshheading:3662285-Male,
pubmed-meshheading:3662285-Middle Aged,
pubmed-meshheading:3662285-Pain,
pubmed-meshheading:3662285-Population Surveillance,
pubmed-meshheading:3662285-Prospective Studies,
pubmed-meshheading:3662285-Recurrence,
pubmed-meshheading:3662285-Risk Factors
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
The clinical evolution of Lyme arthritis.
|
| pubmed:affiliation |
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|