Linked Life Data

3661618

Source:http://linkedlifedata.com/resource/pubmed/id/3661618

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1987-11-18
pubmed:abstractText
The activities of the Krebs cycle (KC), glycolytic pathway (GP), and the hexose monophosphate shunt were studied in endomyocardial biopsies obtained from 25 patients and were related to left ventricular stroke work index (LVSWI). Unexpectedly, KC activity was greater in patients with a reduced LVSWI than in those with a normal or elevated LVSWI. When the cardiac work:KC ratio, defined as LVSWI divided by KC activity, was plotted against LVSWI, the correlation coefficient was 0.86. Cardiac work did not correlate with other metabolic pathways measured. Patients with a reduced LVSWI generated less cardiac work per unit of KC activity than those who had a normal or elevated LVSWI. These data indicate that a reduction in LVSWI below 40 gram-meters/square meter (gm-m/m2) may be associated with either inefficient energy production, inefficient energy utilization, or both.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-9629
pubmed:author
pubmed:issnType
Print
pubmed:volume
294
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
231-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Metabolism in human endomyocardial biopsies and cardiac work.
pubmed:affiliation
Department of Medicine, Louisiana State University Medical Center, Shreveport 71130.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't