Linked Life Data

3661193

Source:http://linkedlifedata.com/resource/pubmed/id/3661193

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1987-11-10
pubmed:abstractText
The ultrastructural alterations in the pulmonary parenchyma were studied in four premature babies with the respiratory distress syndrome who were treated by prolonged mechanical ventilation from 43 to 172 days. Macrophages and fibroblasts passed through a defect of the epithelial basement membrane to encompass the hyaline membrane. Thickening and reduplication of epithelial and capillary basement membrane, varying patterns of epithelial regeneration, i.e., hyperplasia of type II pneumocytes and cuboidal cells, and proliferation of fibroblasts and myofibroblasts were observed in the alveolar walls. In the emphysematous areas, elastic fibers were condensed and thickened, or fragmented. All these changes were more pronounced in premature babies, who underwent concentrations of more than 80% of oxygen and high positive end-expiratory pressures (greater than 30 cm H2O) for long periods.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0001-6632
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1115-26
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Ultrastructural study on the pulmonary parenchyma of the neonates following prolonged mechanical ventilation.
pubmed:affiliation
Department of Pathology, Japanese Red Cross Medical Center, Tokyo.
pubmed:publicationType
Journal Article