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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1979-3-24
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pubmed:abstractText |
The gastrointestinal bleeding during treatment with indomethacin, aspirin, phenylbutazone and sodium salicylate in healthy human subjects was determined. Gastrointestinal blood loss was determined by the Cr51-labelled erythrocyte method. The method was modified by us. Collected stool was incinerated and radioactivity of ashes was determined. Furthermore, rheumatic patients were treated for 4 weeks with indomethacin alone or with indomethacin combined with sodium salicylate. The gastrointestinal blood loss was determined on the last 4 days of treatment. It was found that blood loss was significantly reduced by combined treatment in comparison to monotherapy with indomethacin, while combined treatment had a marked anti-rheumatic effect.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0340-0026
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
610-1
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:365801-Adult,
pubmed-meshheading:365801-Aged,
pubmed-meshheading:365801-Clinical Trials as Topic,
pubmed-meshheading:365801-Female,
pubmed-meshheading:365801-Gastrointestinal Hemorrhage,
pubmed-meshheading:365801-Humans,
pubmed-meshheading:365801-Indomethacin,
pubmed-meshheading:365801-Male,
pubmed-meshheading:365801-Middle Aged,
pubmed-meshheading:365801-Sodium Salicylate
|
pubmed:year |
1978
|
pubmed:articleTitle |
Reduction of indomethacin-induced gastrointestinal blood loss by sodium salicylate in man.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|