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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1987-11-16
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pubmed:abstractText |
Antitumour activity of arabinogalactan peptidoglycan (AP) complex (peptidoglycan and arabinogalactan liberated by an acid or alkaline treatment from Rhodococcus lentifragmentus AN-115 cell wall skeleton) was examined in mice and compared with that of the cell wall skeleton. The growth of syngeneic fibrosarcoma Meth A cells after implantation in BALB/c mice was significantly suppressed by AP complex, and also regressed after intratumoral injection of AP complex on days 1, 4 and 7 after tumour implantation. Although the activity of peptidoglycan was less than that of AP complex, peptidoglycan also showed both tumour-suppressive and regressive activities. Arabinogalactan did not show antitumour activity. It is interesting that peptidoglycan has an important role in the effect against tumours.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1287
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
133
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
369-73
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pubmed:dateRevised |
2005-1-21
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pubmed:meshHeading |
pubmed-meshheading:3655726-Animals,
pubmed-meshheading:3655726-Cell Wall,
pubmed-meshheading:3655726-Fibrosarcoma,
pubmed-meshheading:3655726-Galactans,
pubmed-meshheading:3655726-Mice,
pubmed-meshheading:3655726-Mice, Inbred BALB C,
pubmed-meshheading:3655726-Peptidoglycan,
pubmed-meshheading:3655726-Remission Induction,
pubmed-meshheading:3655726-Rhodococcus
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pubmed:year |
1987
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pubmed:articleTitle |
Antitumour activity of purified arabinogalactan-peptidoglycan complex of the cell wall skeleton of Rhodococcus lentifragmentus.
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pubmed:affiliation |
Research Laboratories, Fujisawa Pharmaceutical Co. Ltd, Osaka, Japan.
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pubmed:publicationType |
Journal Article
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