3654377

Source:http://linkedlifedata.com/resource/pubmed/id/3654377

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001613, umls-concept:C0007776, umls-concept:C0018042, umls-concept:C0022655, umls-concept:C0185026, umls-concept:C0205161, umls-concept:C0205307, umls-concept:C0205440, umls-concept:C0392747, umls-concept:C0521390, umls-concept:C0934502, umls-concept:C2603343
pubmed:dateCreated	1987-11-17
pubmed:abstractText	During normal development in the cat Layer VI cortical neurons, including pyramidal cells, fusiform neurons, inverted pyramidal cells and bipolar neurons located in the gyral regions retain the vertical orientation characteristic of earlier developmental stages. However, Layer VI pyramidal neurons and the subtypes in the sulcal zones develop long horizontal basilar dendrites which seem to form dendritic bundles with those of neighbouring pyramidal cells; in addition, fusiform neurons and bipolar cells are tangentially orientated and horizontal pyramidal neurons appear in place of inverted pyramidal cells in the gyral and intermediate regions. In human cortical malformations, neurons of the external cellular layer (Layers V and VI) in lissencephaly are vertically arranged, but Layer VI neurons in polymicrogyria are tangentially orientated when located in microsulci. These features suggest that neuronal changes occur in Layer VI neurons as a consequence of cortical folding and that cortical folding determines the cellular shape of Layer VI neurons in normal as well as in abnormal development of the cerebral cortex.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-1121923, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-12981610, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-3429306, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-3693064, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-391355, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-4611807, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-4835115, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-4932608, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-5042754, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-64105, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-667399, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-7301112, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-915532, http://linkedlifedata.com/resource/pubmed/commentcorrection/3654377-988918
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0137162
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0021-8782
pubmed:author	pubmed-author:CondonDD, pubmed-author:FábreguesII, pubmed-author:FerresHH
pubmed:issnType	Print
pubmed:volume	152
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	71-82
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:3654377-Animals, pubmed-meshheading:3654377-Cats, pubmed-meshheading:3654377-Cerebral Cortex, pubmed-meshheading:3654377-Fetus, pubmed-meshheading:3654377-Gestational Age, pubmed-meshheading:3654377-Humans, pubmed-meshheading:3654377-Neurons
pubmed:year	1987
pubmed:articleTitle	A Golgi study of the sixth layer of the cerebral cortex. III. Neuronal changes during normal and abnormal cortical folding.
pubmed:affiliation	Departamento de Anatomía Patológica, Hospital Príncipes de España, Spain.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't