Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1987-10-22
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pubmed:abstractText |
1. It is shown that isolated perfused rat and guinea-pig livers can sulphate polyethyleneglycol 200 at rates of about 5 and 10 nmol/g per min, respectively. 2. In the guinea-pig about equal amounts of sulphated polyethyleneglycol 200 appear in the bile and in the perfusate, while in the rat about 99% appears in the latter. 3. Polyethyleneglycols 400 and 1000 are also sulphated in perfused guinea-pig liver but polyethyleneglycol 6000 is not. 4. Polyethyleneglycols are therefore not suitable solvents for xenobiotics which may undergo sulphation because of the likelihood of competition for sulphate.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0049-8254
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
725-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3630207-Animals,
pubmed-meshheading:3630207-Bile,
pubmed-meshheading:3630207-Female,
pubmed-meshheading:3630207-Guinea Pigs,
pubmed-meshheading:3630207-Liver,
pubmed-meshheading:3630207-Male,
pubmed-meshheading:3630207-Perfusion,
pubmed-meshheading:3630207-Polyethylene Glycols,
pubmed-meshheading:3630207-Rats,
pubmed-meshheading:3630207-Species Specificity,
pubmed-meshheading:3630207-Sulfates,
pubmed-meshheading:3630207-Sulfur Radioisotopes
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pubmed:year |
1987
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pubmed:articleTitle |
The metabolic sulphation of polyethyleneglycols by isolated perfused rat and guinea-pig livers.
|
pubmed:publicationType |
Journal Article,
In Vitro
|