|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4822
|
|
pubmed:dateCreated |
1987-10-14
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
A complementary DNA clone derived from rat brain messenger RNA has been isolated on the basis of homology to the human thyroid hormone receptor gene. Expression of this complementary DNA produces a high-affinity binding protein for thyroid hormones. Sequence analysis and the mapping of this gene to a distinct human genetic locus indicate the existence of multiple human thyroid hormone receptors. Messenger RNA from this gene is expressed in a tissue-specific fashion with highest levels in the central nervous system.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0036-8075
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
25
|
|
pubmed:volume |
237
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1610-4
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:3629259-Amino Acid Sequence,
pubmed-meshheading:3629259-Animals,
pubmed-meshheading:3629259-Base Sequence,
pubmed-meshheading:3629259-Brain,
pubmed-meshheading:3629259-DNA,
pubmed-meshheading:3629259-DNA-Binding Proteins,
pubmed-meshheading:3629259-Gene Expression Regulation,
pubmed-meshheading:3629259-Genes,
pubmed-meshheading:3629259-Humans,
pubmed-meshheading:3629259-RNA, Messenger,
pubmed-meshheading:3629259-Rats,
pubmed-meshheading:3629259-Receptors, Thyroid Hormone,
pubmed-meshheading:3629259-Tissue Distribution,
pubmed-meshheading:3629259-Triiodothyronine
|
|
pubmed:year |
1987
|
|
pubmed:articleTitle |
Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
