Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0013710,
umls-concept:C0014912,
umls-concept:C0015914,
umls-concept:C0032975,
umls-concept:C0033308,
umls-concept:C0080103,
umls-concept:C0181904,
umls-concept:C0205242,
umls-concept:C0229671,
umls-concept:C0230463,
umls-concept:C0237753,
umls-concept:C0441889,
umls-concept:C0559956,
umls-concept:C0596972,
umls-concept:C0728873,
umls-concept:C0918012,
umls-concept:C1511572,
umls-concept:C1521743,
umls-concept:C1704646,
umls-concept:C1948023
|
| pubmed:issue |
4
|
| pubmed:dateCreated |
1987-10-13
|
| pubmed:abstractText |
A simple model for monitoring ovarian stimulation in in-vitro fertilization cycles was designed using daily serum levels of 17 beta-oestradiol and progesterone as the only index to determine the day of ovum retrieval. Human chorionic gonadotropin was administered in the evening 2 days after a level of 2500 pmol/l oestradiol in serum was exceeded provided the serum progesterone level was less than 5 nmol/l. Ovarian stimulation was initiated in 128 women scheduled for laparoscopic oocyte retrieval. Twelve cycles (9%) were cancelled before ovum pick up due to sub-optimal hormone levels in serum and five for other reasons. In 107 successful laparoscopies, 616 oocytes (mean 5.8 per laparoscopy) were recovered. The cleavage rate after IVF was 65% in the egg replacement group. In 87 women, a total of 271 cleaved eggs (range 1-6, mean 3.1) were replaced. The most important factor for establishing a pregnancy was the number of eggs replaced at the same time. Clinical pregnancies were achieved after 30% of replacements, increasing to 50% after replacement of 5-6 eggs. The ongoing/delivered pregnancy rate after the 18th week of gestation was 69%. It was concluded that the simple monitoring model used was consistent with a high pregnancy rate and a low rate of cancelled cycles.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0268-1161
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
325-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3624432-Chorionic Gonadotropin,
pubmed-meshheading:3624432-Embryo Transfer,
pubmed-meshheading:3624432-Estradiol,
pubmed-meshheading:3624432-Female,
pubmed-meshheading:3624432-Fertilization in Vitro,
pubmed-meshheading:3624432-Humans,
pubmed-meshheading:3624432-Menstrual Cycle,
pubmed-meshheading:3624432-Oocytes,
pubmed-meshheading:3624432-Ovulation Induction,
pubmed-meshheading:3624432-Pregnancy,
pubmed-meshheading:3624432-Progesterone
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Pregnancy rate in relation to number of cleaved eggs replaced after in-vitro fertilization in stimulated cycles monitored by serum levels of oestradiol and progesterone as sole index.
|
| pubmed:publicationType |
Journal Article
|