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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-9-29
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pubmed:abstractText |
Epidermal mucous metaplasia of cultured skin is known to be induced by excess retinol. Studies were made on whether retinol affects primarily the epidermis or the dermis during retinol-induced epidermal mucous metaplasia of 13-day-old chick embryonic skin in culture. When recombinants of 13-day-old normal epidermis and retinol-treated dermis were cultured for 7 days in chemically defined medium in the absence of retinol, hormones, and serum, they showed altered epidermal differentiation toward secretory epithelium (mucous metaplasia). Thus retinol acted primarily on dermal cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0012-1606
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-62
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3622935-Animals,
pubmed-meshheading:3622935-Cell Communication,
pubmed-meshheading:3622935-Cell Differentiation,
pubmed-meshheading:3622935-Cells, Cultured,
pubmed-meshheading:3622935-Chick Embryo,
pubmed-meshheading:3622935-Epidermis,
pubmed-meshheading:3622935-Hydrocortisone,
pubmed-meshheading:3622935-Organ Culture Techniques,
pubmed-meshheading:3622935-Skin,
pubmed-meshheading:3622935-Vitamin A
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pubmed:year |
1987
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pubmed:articleTitle |
Induction of epidermal mucous metaplasia by culture of recombinants of undifferentiated epidermis and retinol-treated dermis in a chemically defined medium.
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pubmed:publicationType |
Journal Article
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