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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1987-10-9
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pubmed:abstractText |
Reduced glutathione (GSH) has been demonstrated in benign and malignant human breast lesions using a newly developed histofluorescence technique. GSH was present in every lesion and in each case was localised to the epithelium. A semi-quantitative assessment revealed a moderate amount of GSH in normal epithelium and fibroadenoma and a high level in apocrine metaplasia, epitheliosis and intraduct carcinoma. Invasive ductal carcinoma contained a variable amount of GSH. Correlation between fluorescence intensity and histological grade of ductal carcinomas was almost statistically significant but a relationship to oestrogen receptor status was not detected. The rapid assessment of GSH in breast cancer may aid in the selection of optimum chemotherapeutic regimens.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-10448,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-13499785,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-2421885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-2857108,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-2872909,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-2998588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-3463410,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-3536805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-3890714,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-3975906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-4040369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-4065177,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-4092192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-42902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-474272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-5635447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6101309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6135407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6137189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6145717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6149960,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6380705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6586161,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3620301-6891643
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0007-0920
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
605-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3620301-Adolescent,
pubmed-meshheading:3620301-Adult,
pubmed-meshheading:3620301-Aged,
pubmed-meshheading:3620301-Aged, 80 and over,
pubmed-meshheading:3620301-Breast,
pubmed-meshheading:3620301-Breast Diseases,
pubmed-meshheading:3620301-Breast Neoplasms,
pubmed-meshheading:3620301-Glutathione,
pubmed-meshheading:3620301-Histocytochemistry,
pubmed-meshheading:3620301-Humans,
pubmed-meshheading:3620301-Microscopy, Fluorescence,
pubmed-meshheading:3620301-Middle Aged,
pubmed-meshheading:3620301-Receptors, Estrogen
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pubmed:year |
1987
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pubmed:articleTitle |
Glutathione localisation in benign and malignant human breast lesions.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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