Linked Life Data

361519

Source:http://linkedlifedata.com/resource/pubmed/id/361519

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1979-1-24
pubmed:abstractText
Previously, we reported that alpha-MPG and DPA stimulated humoral immuno-responses. In the present work, we investigated the effect of alpha-MPG and DPA on immunosuppression induced by carcinostatic agents including cyclophosphamide (CP), azathioprine (AP), methotrexate (MTX), actinomycin D (AcD) and mitomycin C(MMC) as well as prednisolone (Pred). The formation of hemolytic plaque forming cell (HPFC) in spleen of mice was clearly inhibited by treatment with immunosuppressive agents given s.c. for 5 days from the immunization. When alpha-MPG and DPA were given i.p. concomitantly with immunosuppressive agents, HPFC formation was not inhibited except when the combination of MTX and alpha-MPG was injected. With alpha-MPG, there was a tendency toward disappearance of the leucopenia induced by AP, MMC and Pred.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0015-5691
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
653-61
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
[Effect of alpha-mercaptopropionylglycine (alpha-MPG) and sodium dipropylacetate (DPA) on antibody formation (II). Immunosuppression induced by carcinostatic agents and glucocorticoid (author's transl)].
pubmed:publicationType
Journal Article, English Abstract