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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-9-2
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pubmed:abstractText |
The crystal structure of satellite tobacco necrosis virus has been studied by neutron diffraction at 16 A resolution using the technique of 1H2O/2H2O solvent contrast variation to distinguish between the regions of protein and nucleic acid. The RNA density is essentially localized in a region just inside the protein coat, leading to a significant interaction between the two components. From the appearance of the RNA density we conclude that the protein coat imposes partial icosahedral symmetry on a significant proportion of the nucleic acid. The shape and dimensions of the major part of this density suggests that about 72% of the total RNA could be double-helical in structure. The most important interaction between the two components of the virus occurs between the N-terminal triple-helical arms of the protein subunits and those regions of the RNA density that could have a double-helical secondary structure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-2836
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
194
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-41
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:3612799-Amino Acid Sequence,
pubmed-meshheading:3612799-Fourier Analysis,
pubmed-meshheading:3612799-Neutrons,
pubmed-meshheading:3612799-Plant Viruses,
pubmed-meshheading:3612799-RNA, Viral,
pubmed-meshheading:3612799-Scattering, Radiation,
pubmed-meshheading:3612799-Viral Proteins
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pubmed:year |
1987
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pubmed:articleTitle |
Structure of RNA in satellite tobacco necrosis virus. A low resolution neutron diffraction study using 1H2O/2H2O solvent contrast variation.
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pubmed:publicationType |
Journal Article
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