Linked Life Data

3610824

Source:http://linkedlifedata.com/resource/pubmed/id/3610824

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1987-9-2
pubmed:abstractText
In the presence of NADPH and CuCl2, patulin induced the cleavage of ColE1 DNA and lambda phage DNA in vitro. The DNA-cleaving activity of patulin was concentration dependent. At the lowest concentration of patulin, ColE1 supercoiled DNA was relaxed and the highest concentration induced linearization of the DNA. This activity was inhibited by superoxide dismutase, catalase and radical scavengers, showing involvement of free radicals in the DNA-cleavage. lambda Phage DNA was also degraded by patulin under the same conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-8820
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
692-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Strand scissions of DNA by patulin in the presence of reducing agents and cupric ions.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't