Linked Life Data

3610217

Source:http://linkedlifedata.com/resource/pubmed/id/3610217

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1987-8-28
pubmed:abstractText
The pathogenesis of Candida albicans infection was compared in three inbred strains of mice--CBA/H; C57B1/6J and BALB/c. CBA/H mice developed the most severe lesions, and also showed the weakest inflammatory responses in the popliteal lymph node after challenge with live organisms in the footpad. Nevertheless, this strain cleared candida from the spleen more efficiently than either C57B1/6J or BALB/c mice. This apparently excludes a defect in phagocytosis as the basis for the increased susceptibility. The gene(s) determining susceptibility in CBA/H mice are located outside the major histocompatibility complex (MHC).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0818-9641
pubmed:author
pubmed:issnType
Print
pubmed:volume
65 ( Pt 2)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Murine candidiasis. Pathogenesis and host responses in genetically distinct inbred mice.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't