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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1987-7-30
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pubmed:abstractText |
Thirteen hospitalized cocaine addicts complaining of cocaine craving were given a single dose of bromocriptine, a dopamine agonist, in a randomized, double-blind, placebo-controlled study design. Compared to placebo, bromocriptine caused a significant reduction in craving ratings. These data suggest that bromocriptine may be effective as a new, nonaddictive pharmacological treatment for cocaine addicts and support the notion that functional dopamine depletion occurs with chronic cocaine use. Open trials indicate that low-dose bromocriptine may be useful in cocaine detoxification.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0165-1781
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
261-4
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pubmed:dateRevised |
2008-4-17
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pubmed:meshHeading |
pubmed-meshheading:3602212-Adult,
pubmed-meshheading:3602212-Bromocriptine,
pubmed-meshheading:3602212-Cocaine,
pubmed-meshheading:3602212-Dose-Response Relationship, Drug,
pubmed-meshheading:3602212-Drug Administration Schedule,
pubmed-meshheading:3602212-Female,
pubmed-meshheading:3602212-Humans,
pubmed-meshheading:3602212-Male,
pubmed-meshheading:3602212-Psychological Tests,
pubmed-meshheading:3602212-Substance-Related Disorders
|
pubmed:year |
1987
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pubmed:articleTitle |
Single-dose bromocriptine reverses cocaine craving.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|