|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
1978-12-27
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
The attenuator region of the histidine operon of Escherichia coli K-12 has a potential coding capacity for two peptides, one of 16 amino acids and another of 30 amino acids. This region is followed by a perfect palindrome of 14 base pairs separated by five nucleotides. A G+C-rich region precedes and follows a possible transcription termination sequence. These features are compatible with a model in which active translation of a leader mRNA interferes with transcription termination, thus causing derepression of the histidine operon. The sequence of the region coding for the hypothetical 16-amino acid peptide is of particular relevance because it indicates the site and a possible mechanism of action of histidyl-tRNAhis in regulating histidine gene expression. Seven contiguous histidine codons are present within this sequence: : formula: (see text)
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-1055375,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-1059112,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-1094538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-1103149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-1271462,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-132662,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-135845,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-210156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-265521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-322147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-323237,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-334731,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-337297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-342509,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-344136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-346574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-351195,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4339187,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4366306,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4375069,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4558263,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4599761,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4615040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4902144,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4931745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4934197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4934198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-4947105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-5274471,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-785220,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-834250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-909783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/360215-967673
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0027-8424
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
75
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
4276-80
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:360215-Base Sequence,
pubmed-meshheading:360215-DNA, Recombinant,
pubmed-meshheading:360215-Escherichia coli,
pubmed-meshheading:360215-Genes,
pubmed-meshheading:360215-Genes, Regulator,
pubmed-meshheading:360215-Histidine,
pubmed-meshheading:360215-Operon,
pubmed-meshheading:360215-Transcription, Genetic
|
|
pubmed:year |
1978
|
|
pubmed:articleTitle |
Nucleotide sequence of the attenuator region of the histidine operon of Escherichia coli K-12.
|
|
pubmed:publicationType |
Journal Article
|
