Linked Life Data

3595759

Source:http://linkedlifedata.com/resource/pubmed/id/3595759

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1987-8-17
pubmed:abstractText
The swelling pressure of 115 human corneas was determined using a modified electronic balance modified to simultaneously record the swelling force and the thickness of the stroma. The swelling force was found to follow a straight-line dependence on the stromal thickness when plotted in a double logarithmic scale, which means that the swelling pressure of each cornea could be expressed by a power fit of the form SP = aTb, where SP is swelling pressure, T stromal thickness, and a and b are constants of the cornea. In 45 control corneas swollen in 0.9% NaCl, pH 7.4, 0.01 M Hepes buffer, the mean value (+/- S.D.) of 'a' and 'b' were 7.09 mmHg mm-1 (+/- 2.96) and -3.48 (+/- 0.20), respectively. This corresponded to a mean swelling pressure of 84.0 mmHg at a standard stromal thickness of 0.5 mm. In paired experiments, the swelling pressure was found to be influenced insignificantly (P greater than 0.05) by a number of conditions, including lowering the pH to 4.0, increasing the temperature to 37 degrees C, and increasing the NaCl concentration to 9%. A significant correlation was found between the swelling pressure and the dry weight of the specimen (P less than 0.05), indicating a considerable biological variation of the swelling pressure. It is shown, that this variation may explain the normal variation in human corneal thickness in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0014-4835
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
481-90
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
The swelling pressure of the human corneal stroma as determined by a new method.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't