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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-7-28
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pubmed:abstractText |
The pulse-chase technique was employed to determine the synthesis of the subunits of ligandin (glutathione S-transferase 1-2) by isolated hepatocytes. Ligandin comprised 2.5-3% of the total proteins synthesized. A slightly higher incorporation of [35S]methionine into the 22 k than the 25 k subunit was observed. However, the ratio of [35S]methionine incorporation into the subunits remained constant throughout the chase period, suggesting that, in spite of the considerable sequence homology, the conversion of 25 k to 22 k subunit does not occur in vivo.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
929
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-4
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3593770-Animals,
pubmed-meshheading:3593770-Cells, Cultured,
pubmed-meshheading:3593770-Glutathione Transferase,
pubmed-meshheading:3593770-Liver,
pubmed-meshheading:3593770-Protein Biosynthesis,
pubmed-meshheading:3593770-Protein Processing, Post-Translational,
pubmed-meshheading:3593770-Rats,
pubmed-meshheading:3593770-Sequence Homology, Nucleic Acid
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pubmed:year |
1987
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pubmed:articleTitle |
Synthesis of subunits of ligandin by isolated hepatocytes.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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