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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-7-15
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pubmed:abstractText |
We have identified two mRNAs in rat intestinal mucosa by Northern blot analysis, using cloned cDNAs encoding human placental alkaline phosphatase (PLAP). Probes from both the NH2- and COOH-terminal ends of the human PLAP coding region identified, in rat intestine (especially duodenum), an mRNA of nearly identical size (3 kb) to that found in human placenta. A smaller mRNA (2.7 kb), detected only with the COOH-terminal probe, was more prevalent in jejunum. Following feeding of triacylglycerols, the prevalence of the 2.7 kb mRNA increased over 2-fold. The tissue distribution and response of the 2.7 kb mRNA to fat feeding corresponds exactly with the known behavior of the secreted alkaline phosphatase.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
29
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
363-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3593343-Alkaline Phosphatase,
pubmed-meshheading:3593343-Animals,
pubmed-meshheading:3593343-Cell Membrane,
pubmed-meshheading:3593343-Cloning, Molecular,
pubmed-meshheading:3593343-DNA,
pubmed-meshheading:3593343-Dietary Fats,
pubmed-meshheading:3593343-Female,
pubmed-meshheading:3593343-Humans,
pubmed-meshheading:3593343-Intestinal Mucosa,
pubmed-meshheading:3593343-Intestine, Small,
pubmed-meshheading:3593343-Placenta,
pubmed-meshheading:3593343-RNA, Messenger,
pubmed-meshheading:3593343-Rats
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pubmed:year |
1987
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pubmed:articleTitle |
Fat feeding stimulates only one of the two mRNAs encoding rat intestinal membranous and secreted alkaline phosphatase.
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pubmed:publicationType |
Journal Article
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