Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1987-6-26
pubmed:abstractText
Malformations in twins were studied with the use of a Medical Birth Registry covering nearly all births in Sweden, 1973-1981. A total of 15,427 infants marked twins were identified and the malformation diagnoses were analyzed, comparing rates with the overall rates in the same data source. Problems in ascertainment and interpretation are discussed. No excess of neural tube defects was seen, but hydrocephaly was diagnosed more often in twins than in singletons. This can be partly, but not completely, explained by a higher rate of low-weight infants among twins. An excess was noticed in twins in the rates of cardiac defects, spine defects, gut atresias--notably esophageal and anal atresia--and severe kidney malformations. These are components of the so-called VACTERL syndrome--the last component (limb reductions) being more common in twins than in singletons, though statistical significance was not reached. A relation between monozygotic twinning and this syndrome is tentatively suggested.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-5660
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
167-78
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Congenital malformations in twins: a population study.
pubmed:publicationType
Journal Article