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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1987-7-1
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pubmed:abstractText |
The changes in the activity of the pentose phosphate cycle and the malic enzyme produced by the activation or inhibition of different NADPH-consuming pathways have been studied. The inhibition of the fatty acid synthesis by kynurenate produced a decrease in the flux through the pentose phosphate cycle and a diminution in the malic enzyme pathway. The incubation of the adipocytes in the presence of ter-butyl-hydroperoxide, a compound which is metabolized via a NADPH-consuming pathway, produced a big increase in the pentose phosphate cycle and the malic enzyme activities. The regulation of these NADPH-producing pathways by the NADPH/NADP ratio is discussed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0300-8177
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3587232-Adipose Tissue,
pubmed-meshheading:3587232-Animals,
pubmed-meshheading:3587232-Carmustine,
pubmed-meshheading:3587232-Female,
pubmed-meshheading:3587232-Kinetics,
pubmed-meshheading:3587232-Kynurenic Acid,
pubmed-meshheading:3587232-Malate Dehydrogenase,
pubmed-meshheading:3587232-NADP,
pubmed-meshheading:3587232-Oxidation-Reduction,
pubmed-meshheading:3587232-Pentose Phosphate Pathway,
pubmed-meshheading:3587232-Peroxides,
pubmed-meshheading:3587232-Rats,
pubmed-meshheading:3587232-Rats, Inbred Strains,
pubmed-meshheading:3587232-tert-Butylhydroperoxide
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pubmed:year |
1987
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pubmed:articleTitle |
The NADPH consumption regulates the NADPH-producing pathways (pentose phosphate cycle and malic enzyme) in rat adipocytes.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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