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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
15
|
pubmed:dateCreated |
1987-6-26
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pubmed:abstractText |
Humoral hypercalcemia of malignancy is a common paraneoplastic syndrome which is characterized by hypercalcemia resulting from secretion by tumors of a circulating bone-resorbing factor. Evidence suggests that in many instances this factor is an adenylate cyclase-stimulating protein which shares features with, but is distinct from, parathyroid hormone (PTH). The current report describes the purification to homogeneity from a humoral hypercalcemia of malignancy-associated tumor of a novel, basic, highly potent PTH-like adenylate cyclase-stimulating protein. This factor differs from previously described PTH-like factors with respect to size, amino acid composition, and specific activity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0021-9258
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
25
|
pubmed:volume |
262
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7151-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3584110-Adenylate Cyclase,
pubmed-meshheading:3584110-Amino Acids,
pubmed-meshheading:3584110-Breast Neoplasms,
pubmed-meshheading:3584110-Chromatography, High Pressure Liquid,
pubmed-meshheading:3584110-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:3584110-Humans,
pubmed-meshheading:3584110-Hypercalcemia,
pubmed-meshheading:3584110-Isoelectric Focusing,
pubmed-meshheading:3584110-Molecular Weight,
pubmed-meshheading:3584110-Oxidation-Reduction,
pubmed-meshheading:3584110-Parathyroid Hormone
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pubmed:year |
1987
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pubmed:articleTitle |
Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|