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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-6-29
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pubmed:abstractText |
Ototoxicity is one of the unwanted side effects of cisplatin treatment. The first sign of hearing loss usually appears 3-4 days after the drug administration and occurs primarily in the higher frequencies. One hundred and eighty-six women treated with a moderate dose of cisplatin (50 mg/m2 every 4 weeks) for gynaecological cancer were studied. No significant loss of hearing was detected in the speech frequency range. Since the cisplatin concentration in the inner ear is highest after a single high dose injection, systemic audiometric monitoring is advisable during cisplatin therapy with single high dose regimen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0105-6263
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
359-62
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3583423-Animals,
pubmed-meshheading:3583423-Cisplatin,
pubmed-meshheading:3583423-Cochlea,
pubmed-meshheading:3583423-Female,
pubmed-meshheading:3583423-Genital Neoplasms, Female,
pubmed-meshheading:3583423-Hearing Loss,
pubmed-meshheading:3583423-Hearing Loss, High-Frequency,
pubmed-meshheading:3583423-Humans,
pubmed-meshheading:3583423-Risk
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pubmed:year |
1987
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pubmed:articleTitle |
Ototoxicity of cisplatin.
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pubmed:publicationType |
Journal Article
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