Linked Life Data

3581690

Source:http://linkedlifedata.com/resource/pubmed/id/3581690

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1987-7-9
pubmed:abstractText
Animal studies have shown that arterial baroreflexes are modulated by reflexes originating from the cardiopulmonary volume receptors, and that this modulation consists of a reduction of the inhibitory influence exerted by arterial baroreceptors on the heart and peripheral circulation. This has not been confirmed in man, however, in whom no reduction in the bradycardic response to carotid baroreceptor stimulation has been observed after the mild increase in central venous pressure (right atrial catheter) and cardiopulmonary receptor activity provided by passive leg raising. In seven normotensive subjects carotid baroreceptors were gradedly stimulated by progressively increasing carotid transmural pressure through a neck chamber device, the resulting reflex lengthening in R-R interval being measured in the two-three cardiac cycles immediately after the baroreceptor stimulus. This manoeuvre was performed in control conditions and repeated during a head-out water immersion which increased central venous pressure (right atrial catheter) from 1.5 +/- 0.2 to 12.0 +/- 0.9 mmHg (mean +/- SE), thereby providing a marked increase in the cardiopulmonary receptor stimulus. In the control condition graded stimulation of the baroreceptors caused a progressive lengthening in R-R interval, the maximal effect being + 477.4 +/- 57.2 ms. Immersion increased the R-R interval from 774.2 +/- 3.2 to 961.6 +/- 5.8 ms (P less than 0.01) and reduced mean arterial pressure (cuff measurement) from 96.0 +/- 1.0 to 82.3 +/- 0.9 mmHg. The changes in R-R interval induced by carotid baroreceptor stimulation were virtually identical with those observed in the absence of immersion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0143-5221
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
639-45
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Influence of cardiopulmonary receptors on the bradycardic responses to carotid baroreceptor stimulation in man.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial