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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
219
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pubmed:dateCreated |
1987-7-6
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pubmed:abstractText |
Fifty consecutive patients treated with chymopapain injection for a clinical and radiographic diagnosis of herniated nucleus pulposus were evaluated prospectively. All patients had a prechymopapain computed tomography (CT) scan and a three-month postinjection CT scan. In addition, ten patients (20%) had a six-month postinjection CT scan. All scans were interpreted blindly. Only six patients (12%) had obvious changes in the size of the disc when preinjection and three-month postinjection CT scans were compared. By six months, however, seven of ten patients (70%) had obvious changes in their CT scan. Seven patients (14%) were considered chymopapain treatment failures and were later treated with surgical discectomy. Only two of these seven patients (30%) had obvious changes in their three-month CT scan. Chymopapain injection did not alter the size of the herniated portion of the disc during the first three months after chymopapain injection. A decision to operate for presumed chymopapain failure should therefore be based on clinical grounds, rather than on the three-month CT appearance of the herniated disc.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0009-921X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
120-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3581560-Chymopapain,
pubmed-meshheading:3581560-Humans,
pubmed-meshheading:3581560-Intervertebral Disc Chemolysis,
pubmed-meshheading:3581560-Intervertebral Disc Displacement,
pubmed-meshheading:3581560-Magnetic Resonance Spectroscopy,
pubmed-meshheading:3581560-Prospective Studies,
pubmed-meshheading:3581560-Time Factors,
pubmed-meshheading:3581560-Tomography, X-Ray Computed
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pubmed:year |
1987
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pubmed:articleTitle |
Computed tomography scanning after chymopapain injection for herniated nucleus pulposus. A prospective study.
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pubmed:publicationType |
Journal Article
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