Linked Life Data

3580257

Source:http://linkedlifedata.com/resource/pubmed/id/3580257

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1987-6-26
pubmed:abstractText
There is controversy about the efficacy of sodium restriction in the treatment of hypertension. Short-term restriction of sodium intake in normotensive subjects causes little or no fall in blood pressure. This lack of response of blood pressure to sodium restriction appears to be due, at least in part, to a reactive rise in renin and angiotensin II. In patients with essential hypertension there is suppression of the renin-angiotensin system particularly as blood pressure becomes more severe. With sodium restriction there is less of a rise in renin and angiotensin II compared with normotensive subjects and patients have a greater fall in blood pressure compared with normotensive subjects but the effect is less in mild compared to severe hypertension. As the formation of angiotensin II can now be blocked by the use of a converting enzyme inhibitor, the combination of moderate salt restriction in conjunction with a converting enzyme inhibitor is likely to be more effective in lowering blood pressure than either treatment on its own.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0306-5251
pubmed:author
pubmed:issnType
Print
pubmed:volume
23 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21S-26S
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
The importance of the response of the renin-angiotensin system in determining blood pressure changes with sodium restriction.
pubmed:publicationType
Journal Article