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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1987-6-17
|
| pubmed:abstractText |
Intraventricular and intraperitoneal administration of cocaine and its metabolite norcocaine were studied in adult male rats. Norcocaine (10-100 micrograms) had no behavioral activity following central infusion but proved to be toxic at high doses (50-100 mg/kg) when given peripherally. Cocaine at high doses (100 micrograms), produced possible hypoactivity after central injections but produced significant hyperactivity after peripheral administration (20 mg/kg).
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0091-3057
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
573-5
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3575373-Animals,
pubmed-meshheading:3575373-Cocaine,
pubmed-meshheading:3575373-Injections, Intraperitoneal,
pubmed-meshheading:3575373-Injections, Intraventricular,
pubmed-meshheading:3575373-Male,
pubmed-meshheading:3575373-Motor Activity,
pubmed-meshheading:3575373-Rats,
pubmed-meshheading:3575373-Rats, Inbred F344
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
A comparison of cocaine and its metabolite norcocaine: effects on locomotor activity.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|