rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1987-6-15
|
pubmed:abstractText |
The value of anti-HD IgM as a marker of chronic delta infection was evaluated by correlating its presence in serum with that of HD-Ag in liver cells and with the degree of inflammatory activity. Thirty-six patients with HBsAg-positive chronic hepatitis and anti-HD at high titers were studied. Overall, the liver cells of 26 patients contained HD-Ag and 27 were positive for IgM anti-HD. The correlation between both markers was excellent: 25 cases were positive for both serum anti-HD IgM and intrahepatic HD-Ag and 8 were negative for both markers. There was only 1 HD-Ag-positive patient, who was anti-HD IgM-negative. Two patients were anti-HD IgM-positive and HD-Ag-negative. Histological damage was more severe in anti-HD IgM-positive cases than in those negative for this marker (Knodell's index 13.5 vs 11.9, P less than 0.01). We conclude that anti-HD IgM is a good marker of chronic active delta infection.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0168-8278
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
62-5
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3571933-Adolescent,
pubmed-meshheading:3571933-Adult,
pubmed-meshheading:3571933-Aged,
pubmed-meshheading:3571933-Child,
pubmed-meshheading:3571933-Female,
pubmed-meshheading:3571933-Hepatitis, Chronic,
pubmed-meshheading:3571933-Hepatitis B Antibodies,
pubmed-meshheading:3571933-Hepatitis B Antigens,
pubmed-meshheading:3571933-Hepatitis D,
pubmed-meshheading:3571933-Hepatitis Delta Virus,
pubmed-meshheading:3571933-Hepatitis delta Antigens,
pubmed-meshheading:3571933-Humans,
pubmed-meshheading:3571933-Immunoglobulin M,
pubmed-meshheading:3571933-Liver,
pubmed-meshheading:3571933-Male,
pubmed-meshheading:3571933-Middle Aged
|
pubmed:year |
1987
|
pubmed:articleTitle |
Anti-HD IgM as a marker of chronic delta infection.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|