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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1987-6-12
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pubmed:abstractText |
The long-term effect of lithium treatment on the digestive and absorptive function has been investigated in male albino rats. The uptake of D-glucose, amino acids and activities of cellular and brush border enzymes were evaluated after every 3 months. Significantly increased uptake was observed in 6-month lithium-treated rats. The absorptive capacity (Vmax) for D-glucose increased significantly without alteration in the Michaelis constant. Activities of cellular, brush border membrane disaccharidase, leucine aminopeptidase and Na+,K+-ATPase enzymes were significantly augmented in 6-month lithium-treated animals. The elevation in sucrase activity may be due to induction of enzyme since only Vmax was increased in lithium-treated animals. The present biochemical alterations suggest that long-term lithium ingestion stimulates the small bowel digestive and absorptive functions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0012-2823
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
84-90
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3569679-Amino Acids,
pubmed-meshheading:3569679-Animals,
pubmed-meshheading:3569679-Digestion,
pubmed-meshheading:3569679-Glucose,
pubmed-meshheading:3569679-Intestinal Absorption,
pubmed-meshheading:3569679-Intestine, Small,
pubmed-meshheading:3569679-Kinetics,
pubmed-meshheading:3569679-Lithium,
pubmed-meshheading:3569679-Male,
pubmed-meshheading:3569679-Microvilli,
pubmed-meshheading:3569679-Rats,
pubmed-meshheading:3569679-Rats, Inbred Strains,
pubmed-meshheading:3569679-Sodium
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pubmed:year |
1987
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pubmed:articleTitle |
Effect of lithium ingestion on digestive and absorptive function of rat intestine.
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pubmed:publicationType |
Journal Article
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