Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1987-5-13
pubmed:abstractText
The specific estrogen binding capacity of the MCF-7 cells has been studied throughout the cell cycle. Two days after plating 1-4 X 10(5) cells per well, we observed that cell number, protein concentration and DNA level began to rise but the estrogen binding capacity was lowered. At logarithmic phase the binding increased gradually then sharply to just before confluency. When the cells reached the quiescent phase the estrogen binding capacity fell rapidly. Since estrogen binding capacity of the intact MCF-7 cells varies with different phases in the cell cycle as well as the incubation temperature and time and the plating density, all these factors should be taken into consideration when this cell line is used for hormone studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0304-4602
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
465-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Estradiol binding capacity of breast cancer cell line in correlation with cell cycle.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't