Linked Life Data

3564022

Source:http://linkedlifedata.com/resource/pubmed/id/3564022

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1987-4-29
pubmed:abstractText
The 2-cyanaziridines Ciamexone and Azimexone in doses of 100 and 500 mg/kg lead to a reversible dose-dependent formation of thermolabile hemoglobin and Heinz bodies, a lowered erythrocyte count, and splenomegaly. According to our investigations these effects may have been caused by a covalent binding of the 2-cyanaziridines or their metabolites to globin in the erythrocytes. This binding was shown by gel electrophoresis using 14C-labeled Ciamexone. The change of the globin had no influence on the oxygen affinity of the hemoglobin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0041-008X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
490-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
The binding of ciamexone to globin: its demonstration and some accompanying effects in rats.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't