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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1987-5-12
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pubmed:abstractText |
Various degrees of persistent or paroxysmal paresis involving only the hindlimbs or all four limbs were observed in 3 dogs with hypothyroidism and lymphocytic thyroiditis. Clinical features included lethargy, obesity, alopecia, insidious and progressive paresis, hypotonia, and slow segmental reflexes in 2 dogs. Obesity, alopecia, paroxysmal paresis, and behavior change were observed in the third dog. Laboratory tests indicated that thyroid function was less than normal in all 3 dogs. Abnormal electromyographic potentials and slow motor nerve conduction velocities were found in each dog. Muscle biopsy specimen abnormalities included selective type-II myofiber atrophy in all dogs, whereas one dog had angular atrophy of type-I and type-II myofibers indicative of denervation. A substance that stained with para-aminosalicylic acid was observed within vacuoles of type-I myofibers in one dog. Lymphocytic thyroiditis characterized by lymphocytic infiltration of excised thyroid glands was observed in all dogs.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0003-1488
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
190
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
544-8
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pubmed:dateRevised |
2004-9-20
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pubmed:meshHeading |
pubmed-meshheading:3558092-Animals,
pubmed-meshheading:3558092-Autoantibodies,
pubmed-meshheading:3558092-Dog Diseases,
pubmed-meshheading:3558092-Dogs,
pubmed-meshheading:3558092-Electromyography,
pubmed-meshheading:3558092-Female,
pubmed-meshheading:3558092-Hypothyroidism,
pubmed-meshheading:3558092-Male,
pubmed-meshheading:3558092-Neural Conduction,
pubmed-meshheading:3558092-Neuromuscular Diseases,
pubmed-meshheading:3558092-Thyroid Gland,
pubmed-meshheading:3558092-Thyroiditis, Autoimmune
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pubmed:year |
1987
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pubmed:articleTitle |
Neuromuscular abnormalities associated with hypothyroidism and lymphocytic thyroiditis in three dogs.
|
pubmed:publicationType |
Journal Article,
Case Reports
|