Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-5-21
pubmed:abstractText
The pharmacokinetics and bioavailability of an in vitro controlled release amoxicillin formulation were studied in nine healthy volunteers, in comparison with an intravenous injection and a conventional tablet. The experiment was designed in a crossover fashion. The volunteers received the three formulations on separate occasions. The antibiotic was measured in plasma using a microbiological method. The absolute bioavailability of the two solid dosage forms was estimated comparing non-compartmental parameters. The results indicated that there was no correlation between the in vitro dissolution rate and the pharmacokinetic behavior in the body.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0174-4879
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-100
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Pharmacokinetics and bioavailability of a controlled release amoxicillin formulation.
pubmed:publicationType
Journal Article, Comparative Study