Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1987-6-5
|
pubmed:abstractText |
The initial aim of the present study was to verify in a randomized trial whether the addition of Levamisole, an immunomodulator, could increase the effectiveness of postoperative chemotherapy (MeCCNU + 5-FU) in Dukes C colorectal cancer patients. After entering 29 consecutive patients, the poor results of most studies of adjuvant therapy in colorectal cancer prompted an early end to patient accrual. After 8 years, the lack of significance in survival (48.9 versus 37.3%) and disease-free survival (50 versus 38.8%) between the two treatment arms rules out any improvement associated with Levamisole administration.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0030-2414
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
78-81
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3554085-Adjuvants, Immunologic,
pubmed-meshheading:3554085-Clinical Trials as Topic,
pubmed-meshheading:3554085-Colonic Neoplasms,
pubmed-meshheading:3554085-Drug Therapy, Combination,
pubmed-meshheading:3554085-Female,
pubmed-meshheading:3554085-Fluorouracil,
pubmed-meshheading:3554085-Humans,
pubmed-meshheading:3554085-Levamisole,
pubmed-meshheading:3554085-Male,
pubmed-meshheading:3554085-Random Allocation,
pubmed-meshheading:3554085-Rectal Neoplasms,
pubmed-meshheading:3554085-Remission Induction,
pubmed-meshheading:3554085-Semustine
|
pubmed:year |
1987
|
pubmed:articleTitle |
Adjuvant immunochemotherapy in colorectal cancer Dukes C.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|