Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-5-26
pubmed:abstractText
The distribution of calcitonin gene-related peptide (CGRP) in the A10 dopamine (DA) cell group region of the ventral tegmental area (VTA) of the rat was examined using immunohistochemical techniques. CGRP-like immunoreactivity was localized to axons innervating the rostral and dorsal VTA. Direct administration of CGRP to the VTA of the rat resulted in a dose-related increase in DA utilization in the medial prefrontal cortex, but not other mesocortical, mesolimbic, or striatal DA terminal field regions. These data suggest that CGRP may function to selectively modulate the activity of VTA dopaminergic neurons which innervate the prefrontal cortex.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-74
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Calcitonin gene-related peptide in the ventral tegmental area: selective modulation of prefrontal cortical dopamine metabolism.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't